Use of repetitive DNA sequences to distinguish Mus musculus and Mus caroli cells by in situ hybridization
نویسندگان
چکیده
منابع مشابه
Somatic and germline mosaicism in interspecific chimaeras between Mus musculus and Mus caroli.
Detailed analysis of mosaicism in interspecific chimaeras between Mus musculus and Mus caroli revealed that cells of the two species could coexist and interact normally in all tissues studied. No selection occurred against M. caroli cells during gestation of chimaeras in the M. musculus uterus, but some tissue-specific differential growth of M. musculus and M. caroli cells occurred during postn...
متن کاملInterspecific chimeras in mammals: successful production of live chimeras between Mus musculus and Mus caroli.
Live chimeras between two species of mouse, Mus musculus and Mus caroli, were produced by blastocyst injection. These chimeras were entirely similar to M. musculus in equilibrium with M. musculus chimeras in their somatic tissue organization. This is the first report of completely normal development of interspecific chimeras in mammals.
متن کامل"Interspecific Chimeras in Mammals: Successful Production of Live Chimeras Between Mus musculus and Mus caroli" (1980), by Janet Rossant and William I. Frels
In 1980 Janet Rossant [5] and William I. Frels [6] published their paper, ?Interspecific Chimeras in Mammals: Successful Production of Live Chimeras Between Mus musculus and Mus caroli ,? in Science. Their experiment involved the first successful creation of interspecific mammalian chimeras [7]. Mammalian chimeras [8] are valuable for studying early embryonic development. However, in earlier st...
متن کاملIdentification of embryonic cell lineages in histological sections of M. musculus in-equilibrium M. caroli chimaeras.
An in situ cell marker system has been developed which allows identification of Mus caroli and Mus musculus cells in interspecific chimaeras. A radioactively labelled, cloned DNA probe to M. musculus satellite DNA was hybridized in situ to sections of M. musculus and M. caroli adult tissues. Autoradiography revealed high levels of hybridization to the nuclei of M. musculus cells, but little or ...
متن کاملOntogenesis of serum esterases in Mus musculus.
INTRODUCTION Electrophoretic techniques by which mixtures of isoenzymes, and homologous proteins generally, may be resolved have become valuable tools in developmental biology. They make possible the study of development at the molecular level, in the sense that the differentiation of protein patterns underlies ontogenetic changes and tissue differences. The greater successes of this approach h...
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ژورنال
عنوان ژورنال: Development
سال: 1983
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.73.1.163